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Gajera, Krishna R; Fair, Kathryn L; Moran, Gordon W; Hannan, Nicholas R F; Huelsken, Joerg; Ordóñez-Morán, Paloma
In vitro and in vivo assays for testing retinoids effect on intestinal progenitors' lineage commitments Journal Article
In: Methods Mol. Biol., vol. 2650, pp. 53–61, 2023.
Abstract | Tags: Absorptive, Differentiation, Intestine, Organoids, Retinoids, Secretory, Stem cells
@article{Gajera2023-kn,
title = {In vitro and in vivo assays for testing retinoids effect on
intestinal progenitors' lineage commitments},
author = {Krishna R Gajera and Kathryn L Fair and Gordon W Moran and Nicholas R F Hannan and Joerg Huelsken and Paloma Ord\'{o}\~{n}ez-Mor\'{a}n},
year = {2023},
date = {2023-01-01},
journal = {Methods Mol. Biol.},
volume = {2650},
pages = {53\textendash61},
abstract = {The intestine consists of epithelial cells surrounded by a
complex environment as mesenchymal cells and the gut microbiota.
With its impressive stem cell regeneration capability, the
intestine is able to constantly replenish cells lost through
apoptosis or abrasion by food passing through. Over the past
decade, researchers have identified signaling pathways involved
in stem cell homeostasis such as retinoids pathway. Retinoids are
also involved in cell differentiation of healthy and cancer
cells. In this study, we describe several approaches in vitro and
in vivo to further investigate the effect of retinoids on stem
cells, progenitors, and differentiated intestinal cells.},
keywords = {Absorptive, Differentiation, Intestine, Organoids, Retinoids, Secretory, Stem cells},
pubstate = {published},
tppubtype = {article}
}
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