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Crowley, Jane; Gordon, George S D
Ultra-miniature dual-wavelength spatial frequency domain imaging for micro-endoscopy Journal Article
In: J. Biomed. Opt., vol. 29, no. 2, pp. 026002, 2024.
Abstract | Links | Altmetric | Tags: miniaturization, optical fibers, optical properties, spatial frequency domain imaging
@article{Crowley2024-qi,
title = {Ultra-miniature dual-wavelength spatial frequency domain imaging for micro-endoscopy},
author = {Jane Crowley and George S D Gordon},
doi = {10.1117/1.JBO.29.2.026002},
year = {2024},
date = {2024-02-01},
urldate = {2024-02-01},
journal = {J. Biomed. Opt.},
volume = {29},
number = {2},
pages = {026002},
publisher = {SPIE-Intl Soc Optical Eng},
abstract = {Significance: There is a need for a cost-effective, quantitative
imaging tool that can be deployed endoscopically to better
detect early stage gastrointestinal cancers. Spatial frequency
domain imaging (SFDI) is a low-cost imaging technique that
produces near-real time, quantitative maps of absorption and
reduced scattering coefficients, but most implementations are
bulky and suitable only for use outside the body. Aim: We aim to
develop an ultra-miniature SFDI system comprising an optical
fiber array (diameter 0.125 mm) and a micro camera (1$times$1
mm package) to displace conventionally bulky components, in
particular, the projector. Approach: First, we fabricated a
prototype with an outer diameter of 3 mm, although the
individual component dimensions could permit future packaging to
a 90% are feasible for detecting simulated squamous cell
carcinoma. Conclusions: This device shows promise as a
cost-effective, quantitative imaging tool to detect variations
in optical absorption and scattering as indicators of cancer.},
keywords = {miniaturization, optical fibers, optical properties, spatial frequency domain imaging},
pubstate = {published},
tppubtype = {article}
}
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