Publications

@article{Wilde2020-td,

title = {Natural course of adult-onset vitelliform lesions in eyes with 

 and without comorbid subretinal drusenoid deposits},

author = {Craig Wilde and Mary Awad and Konstantinos Giannouladis and Arun Lakshmanan and Aaron Ming-Hon Yeung and Harminder Dua and Winfried M K Amoaku},

year  = {2020},

date = {2020-06-01},

journal = {Int. Ophthalmol.},

volume = {40},

number = {6},

pages = {1501\textendash1508},

publisher = {Springer Science and Business Media LLC},

abstract = {PURPOSE: Adult vitelliform lesions (AVL) are associated with age 

 related macular degeneration (AMD) and subretinal drusenoid 

 deposits (SRDD). We evaluated the natural course of AVL, 

 assessing the influence of SRDD on disease progression, visual 

 function and incidence of macular atrophy (MA) and choroidal 

 neovascular membranes (CNVM). METHODS: A retrospective cohort 

 study was conducted between January 2011 and March 2016. 

 Demographic, clinical and imaging data from 26 consecutive AVL 

 patients were analysed following case note review. Optical 

 coherence tomography images were graded for SRDD and patients 

 divided into those with/without SRDD. Outcomes included 

 presenting/changes in best corrected visual acuity (BCVA) and 

 incidence of MA/CNVM. RESULTS: Mean age was 78.6 $±$ 7.6 

 years. Mean follow-up was 51.5 $±$ 25.6 months. Twelve 

 patients (46.2%) had SRDD at presentation with 3 more (11.5%) 

 developing them. Subjects with SRDD were older (mean 81.7 $±$ 6.1 years vs 74.3 $±$ 7.6 year},

keywords = {Adult-onset   vitelliform lesions, Adult-onset foveomacular vitelliform dystrophy, Prognosis, Pseudodrusen, Reticular drusen, Subretinal drusenoid deposits},

pubstate = {published},

tppubtype = {article}

}