Publications

@article{Pearcy2025-kj,

title = {Adapting OptCouple to identify strategies with increased  product yields in community cohorts of E. coli},

author = {Nicole Pearcy and Jamie Twycross},

doi = {10.3390/metabo15050309},

year  = {2025},

date = {2025-05-01},

urldate = {2025-05-01},

journal = {Metabolites},

volume = {15},

number = {5},

abstract = {BACKGROUND: Microbesas chemical factories provide an alternative 

 sustainable approach for producing platform chemicals. Until 

 recently, most efforts have involved engineering heterologous 

 pathways into a single microbial chassis to maximise its 

 production of a target chemical. More recently, cohorts of 

 microbes have been used to engineer microbial communities to 

 achieve higher yields than achieved in a single chassis.},

keywords = {community microbial designs, guaranteed product   yields, multi-directional dependent models, OptCouple},

pubstate = {published},

tppubtype = {article}

}