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Li, Yan; Mather, Melissa; Metje, Nicole; Cacciapuoti, Angela Sara; Criscuolo, Lorenza; d'Avossa, Laura; Muramatsu, Mayu; Maragkou, Maria
Women in quantum Journal Article
In: Commun Eng, vol. 4, no. 1, pp. 112, 2025.
Links | Altmetric | Tags: quantum optics, quantum sensing
@article{Li2025-kr,
title = {Women in quantum},
author = {Yan Li and Melissa Mather and Nicole Metje and Angela Sara Cacciapuoti and Lorenza Criscuolo and Laura d\'Avossa and Mayu Muramatsu and Maria Maragkou},
doi = {10.1038/s44172-025-00449-8},
year = {2025},
date = {2025-06-01},
urldate = {2025-06-01},
journal = {Commun Eng},
volume = {4},
number = {1},
pages = {112},
keywords = {quantum optics, quantum sensing},
pubstate = {published},
tppubtype = {article}
}
Radu, Valentin; Price, Joshua Colm; Levett, Simon James; Narayanasamy, Kaarjel Kauslya; Bateman-Price, Thomas David; Wilson, Philippe Barrie; Mather, Melissa Louise
Dynamic quantum sensing of paramagnetic species using nitrogen-vacancy centers in Diamond Journal Article
In: ACS Sens., vol. 5, no. 3, pp. 703–710, 2020.
Abstract | Tags: diamond, lanthanides, nitrogen vacancy, paramagnetic, photoluminescence, quantum sensing
@article{Radu2020-iu,
title = {Dynamic quantum sensing of paramagnetic species using
nitrogen-vacancy centers in Diamond},
author = {Valentin Radu and Joshua Colm Price and Simon James Levett and Kaarjel Kauslya Narayanasamy and Thomas David Bateman-Price and Philippe Barrie Wilson and Melissa Louise Mather},
year = {2020},
date = {2020-03-01},
journal = {ACS Sens.},
volume = {5},
number = {3},
pages = {703\textendash710},
publisher = {American Chemical Society (ACS)},
abstract = {Naturally occurring paramagnetic species (PS), such as free
radicals and paramagnetic metalloproteins, play an essential
role in a multitude of critical physiological processes
including metabolism, cell signaling, and immune response. These
highly dynamic species can also act as intrinsic biomarkers for
a variety of disease states, while synthetic paramagnetic probes
targeted to specific sites on biomolecules enable the study of
functional information such as tissue oxygenation and redox
status in living systems. The work presented herein describes a
new sensing method that exploits the spin-dependent emission of
photoluminescence (PL) from an ensemble of nitrogen-vacancy
centers in diamond for rapid, nondestructive detection of PS in
living systems. Uniquely this approach involves simple
measurement protocols that assess PL contrast with and without
the application of microwaves. The method is demonstrated to
detect concentrations of paramagnetic salts in solution and the
widely used magnetic resonance imaging contrast agent gadobutrol
with a limit of detection of less than 10 attomol over a 100
μm $times$ 100 μm field of view. Real-time monitoring
of changes in the concentration of paramagnetic salts is
demonstrated with image exposure times of 20 ms. Further,
dynamic tracking of chemical reactions is demonstrated via the
conversion of low-spin cyanide-coordinated Fe3+ to hexaaqua Fe3+
under acidic conditions. Finally, the capability to map
paramagnetic species in model cells with subcellular resolution
is demonstrated using lipid membranes containing
gadolinium-labeled phospholipids under ambient conditions in the
order of minutes. Overall, this work introduces a new sensing
approach for the realization of fast, sensitive imaging of PS in
a widefield format that is readily deployable in biomedical
settings. Ultimately, this new approach to nitrogen
vacancy-based quantum sensing paves the way toward minimally
invasive real-time mapping and observation of free radicals in
in vitro cellular environments.},
keywords = {diamond, lanthanides, nitrogen vacancy, paramagnetic, photoluminescence, quantum sensing},
pubstate = {published},
tppubtype = {article}
}
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