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Fuentes-Domínguez, Rafael; Yao, Mengting; Hardiman, William; Cavera, Salvatore Iii La; Setchfield, Kerry; Pérez-Cota, Fernando; Smith, Richard J; Clark, Matt
Parallel imaging with phonon microscopy using a multi-core fibre bundle detection Journal Article
In: Photoacoustics, vol. 31, no. 100493, pp. 100493, 2023.
Abstract | Tags: Parallel measurements, Phonon microscopy, Picosecond ultrasonics, Time-domain Brillouin scattering
@article{Fuentes-Dominguez2023-ls,
title = {Parallel imaging with phonon microscopy using a multi-core fibre
bundle detection},
author = {Rafael Fuentes-Dom\'{i}nguez and Mengting Yao and William Hardiman and Salvatore Iii La Cavera and Kerry Setchfield and Fernando P\'{e}rez-Cota and Richard J Smith and Matt Clark},
year = {2023},
date = {2023-06-01},
journal = {Photoacoustics},
volume = {31},
number = {100493},
pages = {100493},
publisher = {Elsevier BV},
abstract = {In this paper, we show a proof-of-concept method to parallelise
phonon microscopy measurements for cell elasticity imaging by
demonstrating a 3-fold increase in acquisition speed which is
limited by current acquisition hardware. Phonon microscopy is
based on time-resolved Brillouin scattering, which uses a
pump-probe method with asynchronous optical sampling (ASOPS) to
generate and detect coherent phonons. This enables access to the
cell elasticity via the Brillouin frequency with sub-optical
axial resolution. Although systems based on ASOPS are typically
faster compared to the ones built with a mechanical delay line,
they are still very slow to study real time changes at the
cellular level. Additionally, the biocompatibility is reduced
due to long light exposure and scanning time. Using a multi-core
fibre bundle rather than a single channel for detection, we
acquire 6 channels simultaneously allowing us to speed-up
measurements, and open a way to scale-up this method.},
keywords = {Parallel measurements, Phonon microscopy, Picosecond ultrasonics, Time-domain Brillouin scattering},
pubstate = {published},
tppubtype = {article}
}
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